Academics

Bio

Dr. Mukul S. Godbole is an early-stage, independent cancer researcher who employs logical and functional genomics approaches to investigate the mechanisms involved in steroid hormone and receptor-mediated triple-negative breast cancer. He earned his Ph.D. from the Homi Bhabha National Institute for the research he conducted at ACTREC-Tata Memorial Centre, Mumbai, where he identified the genomic and proteomic targets of progesterone in breast cancer. Dr. Godbole has over six years of teaching experience in Biology, one year of post-PhD research experience, and three years of experience as a Freelance Science Editor in Clinical Oncology/Cancer Research with Cactus Communications Pvt. Ltd. He also serves as an Editorial Board Member for Cancer Reports, a Guest Editor for Cancer and Microbiome Special Issue, an Early Career Reviewer for Journal of Biological Chemistry, and a Peer Reviewer for multiple journals, including Cancer Reports, Experimental Cell Research, Cellular Signalling, Heliyon, PLoS ONE, and STAR Protocols.

Research Area

Basic and translational research, breast cancer, functional genomics, steroid hormones and receptors, cancer cell biology, noncoding RNAs in cancer, cancer cell migration-invasion-metastasis, gut and oral microbiome.

Publication

1. Yadav N, Sunder R, Desai S, Dharavath B, Chandrani P, Godbole M, Dutt A. Progesterone modulates the DSCAM-AS1/miR-130a/ESR1 axis to suppress cell invasion and migration in breast cancer. Breast Cancer Res. 2022;24(1):97. doi: 10.1186/s13058-022-01597-x. PMID: 36578092. (IF: 8.408).
2. Godbole M, Togar T, Patel K, Dharavath B, Yadav N, Janjuha S, Gardi N, Tiwary K, Terwadkar P, Desai S, Prasad R, Dhamne H, Karve K, Salunkhe S, Kawle D, Chandrani P, Dutt S, Gupta S, Badwe RA, Dutt A. Up-regulation of the kinase gene SGK1 by progesterone activates the AP-1-NDRG1 axis in both PR-positive and -negative breast cancer cells. J Biol Chem. 2018;293(50):19263-19276. doi: 10.1074/jbc.RA118.002894. Epub 2018 Oct 18. PMID: 30337371. (IF: 5.485).
3. Godbole M, Chandrani P, Gardi N, Dhamne H, Patel K, Yadav N, Gupta S, Badwe R, Dutt A. miR-129-2 mediates down-regulation of progesterone receptor in response to progesterone in breast cancer cells. Cancer Biol Ther. 2017;18(10):801-805. doi: 10.1080/15384047.2017.1373216. PMID: 28876975. (IF: 4.875).
4. Godbole M, Tiwary K, Badwe R, Gupta S, Dutt A. Progesterone suppresses the invasion and migration of breast cancer cells irrespective of their progesterone receptor status - a short report. Cell Oncol (Dordr). 2017;40(4):411-417. doi: 10.1007/s13402-017-0330-z. PMID: 28653288. (IF: 7.051).
5. Sikder S, Kumari S, Kumar M, Sen S, Singhal NB, Chellappan S, Godbole M, Chandrani P, Dutt A, Gopinath KS, Kundu TK. Chromatin protein PC4 is downregulated in breast cancer to promote disease progression: Implications of miR-29a. Oncotarget. 2019;10(64):6855-6869. doi: 10.18632/oncotarget.27325. PMID: 31839879. (IF: 5.168).

Google Scholar Link

https://scholar.google.com/citations?user=yFN3gaQAAAAJ&hl=en

Scopus Link

https://www.scopus.com/authid/detail.uri?authorId=57210650570

Orcid Link

https://orcid.org/0000-0003-0711-8696